Importance of the Cell Block Technique in Diagnosing Patients with NSCLC with Pleural Effusion

Our century is a century that struggle with cancer is continuing. In this struggle, along with effective treatment methods, developing early and easy diagnosis techniques are crucial. Cytological examination of the pleural effusion fluid is the most common diagnosis technique (Rodriguez et al., 1989; Biesterfeld et al., 2014). The cytological examination of the pleural effusion fluid is important in terms of diagnosis, prognosis and stating of malignant lesions (Nance et al., 1991; Cusumano et al., 2007). In conventional cytology, discrimination of the reactive mesothelium cells and malignant cells is the most important diagnostic problem (Carpagnano et al., 2012). The different techniques that different laboratories use, the overlapping of the cells, overcrowded cell communities, loss of cells are all reasons why conventional technique has a low sensitivity. Cell-block technique is one of the oldest techniques that is used in evaluating serous fluids (Basnet et al., 2001). Today, in cell-block preparation, 10% formalin is used in fixation. The superiority of this